Levothyroxine shortage

Xanax (alprazolam) Zoloft (sertraline) Zyrtec (cetirizine) Levothyroxine alcohol/food interactions. There are 3 alcohol/food interactionswith levothyroxine. Levothyroxine disease interactions. There are 5 disease interactionswith levothyroxine which include: adrenal insufficiency. cardiovascular disease.

For people on long-term thyroid hormone replacement, that works out to about $760 a year. Health insurance can help cover much of this cost, but copays will vary based on your insurance plan and its formulary. Synthroid copay costs for Medicare patients range from $6 to $44 per month. Switching to generic Synthroid can significantly reduce costs.Serious shortage protocols (SSPs) In February 2019, the Human Medicines Regulations 2012 were changed to introduce SSPs. Further changes came into force in July 2019, in the NHS (amendments relating to serious shortage protocols) Regulations 2019. If the Department of Health and Social Care (DHSC) decide there is a serious shortage of a ...Giving daily levothyroxine pills to people with a mild abnormality called subclinical hypothyroidism offers no benefit, a review of 21 clinical trials suggests. ... Prescription drug shortage ...Specifications will be determined upon review of the abbreviated new drug application (ANDA). Explanation: FDA has concluded that levothyroxine sodium is a narrow therapeutic index (NTI) drug based on the following evidence: The range between serum levothyroxine therapeutic and toxic concentrations is narrow; Some levothyroxine-associated ...Jan 11, 2018. Walmart pharmacies are reporting a Levothyroxine shortage, due to the recent hurricane that struck Puerto Rico. Levothyroxine is one of the drugs on Walmart’s $4 Generic List. Its price will be temporarily increased to $9 for a 30-day supply and $24 for a 90-day supply. Even with the price increase, Walmart remains to have the ...See the pediatric dosage chart below for details. Recommended starting dosage ranges are given as micrograms per kilogram of body weight (mcg/kg) and are taken once per day. If your child's* age ...

LEVOXYL shortage. We have been made aware of a shortage of Levoxyl (levothyroxine sodium - Pfizer). We have been informed that this is a temporary shortage due to packaging related issues, but no resolution date has been stated. You may receive calls from your patients and their pharmacies about this shortage.LEVOTHYROXINE SODIUM. Shortage reports. Brand name Strength Dosage Status Date Created Date Updated Reports ELTROXIN: 100MCG ... Avoided shortage 2017-11-20: 2017-11-23: 29739: SYNTHROID: 100MCG TABLET Avoided shortage 2020-08-20: 2020-10-14: 122560: SYNTHROID: 100MCG TABLET ...If you are taking 100mcg of Synthroid you may find benefit in taking 2, 50mcg tablets instead of 1, 100mcg tablet. #2. Consider switching from Levothyroxine/Synthroid to Tirosint – Tirosint is a cleaner thyroid medication with only 4 ingredients (3 of which are inactive ingredients).global levothyroxine sodium market size was USD 3513.1 million in 2020. As per our research, the market is projected to touch USD 4253.7 million by 2027, exhibiting a CAGR of 2.8% during the ...SYNTHROID: Common or Proper name: LEVOTHYROXINE SODIUM: Company Name: BGP PHARMA ULC: Market Status: MARKETED: Active Ingredient(s) ... Packaging size: 90BT, 1000BT: ATC code: H03AA: ATC description: THYROID PREPARATIONS: Reason for shortage: Disruption of the manufacture of the drug. Anticipated start date: 2021-02-24: Actual start date: 2020 ...Hypothyroidism can be treated with levothyroxine, which is produced from different manufacturers. In 2016, the manufacturer of the levothyroxine brand Thyrax experienced an interruption in production that required many Dutch patients to change their levothyroxine supplier. The current study examined the effect of the shortage of the levothyroxine brand Thyrax in the Netherlands and subsequent ...

June 28, 2021. One of the most common prescription drugs in America – levothyroxine – is used by people with underactive thyroid glands, also known as hypothyroidism. However, a new study by Mayo Clinic researchers says the majority of people were initiated on levothyroxine for mild subclinical hypothyroidism or for no apparent thyroid ...The internet has revolutionized the way we search for information. Whether you’re looking for a new job, a restaurant to eat at, or a church to attend, there’s no shortage of onlin...Oct 31, 2016 · Common factors that can necessitate levothyroxine dose adjustments include lack of medication persistence, changes in levothyroxine formulation, dosage errors, concomitant medical conditions/medications, body mass changes, and dietary habits. Levothyroxine is a drug with a narrow therapeutic index and its absorption is dependent on gastric pH. Getting three months filled at a time rather than monthly at least makes the annoyance more rare. It might depend on where you live, increased hypothyroidism cases (not sure if this is a thing right now), and the company itself. Where I live, I’m experiencing similar issues with a lot of RX at CVS. Dr. Izabella Wentz. Dr. Izabella Wentz, PharmD, FASCP, is a clinical pharmacist, New York Times Bestselling Author, and a pioneering expert in lifestyle interventions for treating Hashimoto's Thyroiditis. She received a Doctor of Pharmacy degree from the Midwestern University Chicago College of Pharmacy at the age of 23, and has worked as a ...

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Thyroid hormone replacement is one of the most commonly prescribed and cost effective treatments for a chronic disease. There have been recent changes in community prescribing policies in many areas of the UK that have changed patient access to necessary medications. This study aimed to provide a picture of thyroid hormone …Levothyroxine is a synthetic thyroid hormone medication that treats hypothyroidism. In addition to the generic, it’s available as the brand-name medications Levoxyl, Euthyrox, Levo-T, Unithroid, Synthroid, and Tirosint. The average retail price for a 1-month supply of generic levothyroxine ranges from $4 to $27.Levothyroxine shortage statement. Walmart has released a statement to its customers filling Levothyroxine: Attention Levothyroxine Customers: Due to the recent hurricane in Puerto Rico, where Levothyroxine is manufactured, there's a temporary shortage and a cost increase to pharmacies. Effective December 8, 2017, your price will increase ...The dosage of levothyroxine needs to be tailored for each individual and there is a fine line between... more. Euthyrox has an average rating of 1.7 out of 10 from a total of 163 ratings on Drugs.com. 6% of reviewers reported a positive effect, while 92% reported a negative effect. Levothyroxine has an average rating of 5.1 out of 10 from a ...Nature-Throid® and WP Thyroid® (thyroid tablets, USP) is composed of liothyronine and levothyroxine, and are used to treat hypothyroidism (underactive thyroid). The products subject to recall ...shortages, across the nation. ASHP updates the drug shortage database with every drug shortage reported as soon as it is investigated and confirmed, usually within 24-72 hours.7 ASHP works closely with officials in the FDA's Drug Shortages Program and regularly updates FDA staff, Congress, and other policymakers on emerging shortages.

Levothyroxine [79] is a synthetic thyroid hormone naturally secreted by the follicular cells of the thyroid gland [80,81].It is exploited to treat thyroid hormone deficiency, and occasionally to prevent the recurrence of thyroid cancer. Recently, Anota et al. [82] studied the interaction between the levothyroxine (C 15 H 11 N I4 O 4) molecule and (5,5) BNNTs, using DFT where the exchange ...They have a 90% higher likelihood of a shortage event than the average drug product, according to one analysis. Shortages are expensive, too. The HHS office found that there is a 16.6% increase in ...Current American Thyroid Association guidelines recommend that women who are treated with levothyroxine for hypothyroidism and planning for pregnancy should have their TSH levels checked before becoming pregnant and to have their levothyroxine dose adjusted to keep TSH below 2.5mIU/L. In general, the levothyroxine dose needs to be increased ... But in the last few years there have been insulin shortages, baby formula shortages, microchip shortages, and many others. My fear is that levothyroxine could be another shortage soon. The lifespan of a levothyroxine pill is only 6 months so it's not a situation where you can stockpile them. No specific predictable reason. Just general fear. Public Meeting for Levothyroxine Sodium Therapeutic Equivalence May 23, 2005, Washington, DC; 2006 Endocrinologic and Metabolic Drugs Advisory Committee; Content current as of: 03/04/2022.LEVOTHYROXINE SODIUM. Shortage reports. Brand name Strength Dosage Status Date Created Date Updated Reports LEVOTHYROXINE SODIUM FOR INJECTION: ... Avoided shortage 2021-02-17: 2021-04-07: 134246: SYNTHROID: 75MCG TABLET Resolved 2021-03-02: 2021-04-07: 134941: SYNTHROID: 125MCG TABLET ...The reason patients have been getting levothyroxine from different manufacturers is due to shortages, particularly of Mylan medicines. Believe me, pharmacists want patients to stay on levothyroxine from the same company. However, when the product is unavailable, we have to switch manufacturers, or the patient gets nothing.Levothyroxine sodium is a drug approved by the FDA as an oral and injectable prescription thyroid hormone medication that is used to treat underactive thyroid (hypothyroidism) and other conditions.Hypothyroidism is a medical term that refers to any state in which a person's thyroid hormone production is below normal. This medication replaces or provides thyroid hormone support, which is ...

3 in shortage.14 According to a May 2023 study from the Office of the Assistant Secretary for Planning and Evaluation (ASPE), "[t]he average drug shortage affects at least a half a million consumers," triggering both direct and indirect costs.15 Medicare-aged Americans represent roughly one-third of those impacted.

Synthroid is a brand-name medication. It’s a human-made version of a naturally occurring thyroid hormone called thyroxine (T4). T4 is made by the thyroid gland in your neck. Once it’s made, your body turns this into triiodothyronine hormone (T3) as needed, which is the active version of the hormone. The advantage to taking T4 over T3 …Most authorities therefore recommend use of T 4 alone. 2, 7, 13, 14, 27 An initial levothyroxine dose of 100 to 500 μg administered intravenously should be followed by 75 to 100 μg administered ...May 27, 2021 ... levothyroxine, which is used to treat hypothyroidism (under-active thyroid gland). More recently, SSPs have also been issued for: Competact ...IBSA Pharma Inc. is voluntarily recalling 27 lots of TIROSINT®-SOL (levothyroxine sodium) Oral Solution to the consumer level. This voluntary recall has been initiated because these lots may be ...Box 1: Medicines shortages: a widespread and persistent problem • In the U.S., new drug shortages rose from 70 in 2006 to a high of 267 in 2011. The total number of new and ongoing shortages crossed the 450 mark in 2012 (1). In an example cited by FIP, shortages cost U.S. hospitals US$ 416 million, i.e. US$Levothyroxine ( Euthyrox, Synthroid, Levo-T, Unithroid, Levoxyl) is an inexpensive drug used to treat hypothyroidism. It also treats thyroid cancer. This drug is more popular than comparable drugs. Generic levothyroxine is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower. The most common ...Levothyroxine is also used together with surgery and radioiodine treatment to treat a type of thyroid cancer called thyroid-dependent well-differentiated thyroid cancer. This medicine is available only with your doctor's prescription. This product is available in the following dosage forms: Capsule, Liquid Filled.LEVOTHYROXINE SODIUM. Shortage reports. Brand name Strength Dosage Status Date Created Date Updated Reports LEVOTHYROXINE SODIUM FOR INJECTION: 500MCG POWDER FOR SOLUTION Resolved 2023-03-22: 2023-07-20: 187645: LEVOTHYROXINE SODIUM FOR INJECTION ...June 28, 2021. One of the most common prescription drugs in America – levothyroxine – is used by people with underactive thyroid glands, also known as hypothyroidism. However, a new study by Mayo Clinic researchers says the majority of people were initiated on levothyroxine for mild subclinical hypothyroidism or for no apparent thyroid ...

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SYNTHROID: Common or Proper name: LEVOTHYROXINE SODIUM: Company Name: BGP PHARMA ULC: Market Status: MARKETED: Active Ingredient(s) ... Packaging size: 90BT, 1000BT: ATC code: H03AA: ATC description: THYROID PREPARATIONS: Reason for shortage: Disruption of the manufacture of the drug. Anticipated start date: 2020-10-21: Actual start date: 2020 ...A total of 11/125 (8.8%) had adverse effects from Armour Thyroid while 4/125 (3.2%) of patients on levothyroxine had adverse effects to the medication. The difference of 5.6% leaned toward clinical significance and trended toward being statistically significant (p value=0.06, CI -0.4842% to 12.1677%). Our research shows that patients generally ...Mercury Pharmaceutical Levothyroxine. I seem to have some problems sourcing my usual brand of Levothyroxine 100mcg which is by Mercury Pharmaceutical. I have been using this brand for many years and having had problems with other brands I wish to stick with it. Many of the usual pharmacies I use have said they have not got any stock and/or have ...John Yang: All year long, drug shortages have disrupted hospitals and pharmacies. Medications for ADHD, chemotherapy and diabetes, among others, have constantly been in low supply. And now RSV ...The company’s analyses show a slight decrease below 95.0% of its labeled amount in levothyroxine sodium (T4) for some lots. This recall does not apply to TIROSINT® (levothyroxine sodium) capsules.Biden's plan to stem drug shortages involves using the Defense Production Act, a Cold War-era law, to bring drug making back to the U.S.Levothyroxine sodium powder for solution for injection, Par Pharmaceuticals, 200 mcg single dose vial, NDC 42023-0202-01. Reason for the Shortage. Fresenius Kabi has levothyroxine injection available. Par did not provide a reason for the shortage. Piramal Critical Care discontinued levothyroxine injection in late-2022.For oral dosage form (solution): For hypothyroidism: Adults and children older than 12 years of age (growth and puberty complete)—Dose is based on body weight and must be determined by your doctor. The dose is usually 1.6 microgram (mcg) per kilogram (kg) of body weight per day but may be less in older adults.100mcg of levothyroxine is about 60mg of armour -- you need to work with a doctor to make sure the conversion works out for you and that labs are appropriate. Read More. This means that each mcg of T3 is equal to 4 mcg of T4. Since Armour Thyroid contains 39 mcg of T4 and 9 mcg of T3, if you convert the T3 to equivalent T4 (multiply by 4), then ... ….

Synthroid is a brand-name medication. It’s a human-made version of a naturally occurring thyroid hormone called thyroxine (T4). T4 is made by the thyroid gland in your neck. Once it’s made, your body turns this into triiodothyronine hormone (T3) as needed, which is the active version of the hormone. The advantage to taking T4 over T3 …Synthroid is a brand-name medication. It’s a human-made version of a naturally occurring thyroid hormone called thyroxine (T4). T4 is made by the thyroid gland in your neck. Once it’s made, your body turns this into triiodothyronine hormone (T3) as needed, which is the active version of the hormone. The advantage to taking T4 over T3 is ...Levothyroxine doses were prepared using a 100 microgram (µg) reconstituted vial. Wholesale acquisition cost (WAC) was used as the reference for medication costs of the IV levothyroxine 100-µg reconstituted vial and the levothyroxine oral tablets. The WAC price of levothyroxine sodium as of June 2019 was $78.59 for the …Mar 17, 2017 ... This means that TSH levels alone are useless for deciding whether someone with pituitary disease has developed a pituitary-thyroid deficiency or ...Key principles for responding to shortages/stock outs The impact of a shortage or stock out of medicines is lack of access to medicines for patients, with resulting poor health outcomes. Therefore, a patient-centred approach to managing shortages and stock outs is needed. Transparency should be at the core of the approach,Pfizer Safety Reporting Site. LEVOXYL® (levothyroxine sodium) Dosage Forms and Strengths 3 DOSAGE FORMS AND STRENGTHS LEVOXYL tablets are oval, color-coded and, potency marked available as follows: Strength (mcg) Color Tablet Markings 25 Orange 25 50 White 50 75 Purple 75 88 Olive 88 100 Yellow 100 112 Rose 112 125 Light.We have been made aware of a shortage of Levoxyl (levothyroxine sodium – Pfizer). We have been informed that this is a temporary shortage due to packaging …Introduction. Hypothyroidism is a common disorder, with a prevalence of approximately 5% and an incidence of approximately 250/100,000 per year in the adult population, but both prevalence and incidence keep rising (1, 2).Consequently, levothyroxine (l-T4) is one of the most prescribed medications.In the United States, l-T4 ranked first in the year 2014 list of top medicines by prescription ... Levothyroxine shortage, Thyroid Drug Shortages Creating Consternation, Confusion. By staff. In September 2020, Acella Pharmaceuticals LLC recalled two lots of NP Throid and RLC …, Published on October 28, 2021. Key takeaways: A drug shortage can happen for many reasons. The specific reason impacts how long a supply problem might last. The FDA …, Levothyroxine sodium solution for injection, Fresenius Kabi, 20 mcg/mL (100 mcg), 5 mL single dose vial, NDC 63323-0885-10. Levothyroxine sodium powder for solution for injection, Par Pharmaceuticals, 200 mcg single dose vial, NDC 42023-0202-01. Levothyroxine sodium powder for solution for injection, Par Pharmaceuticals, 500 mcg single dose ..., Levothyroxine is a synthetic thyroid hormone medication that treats hypothyroidism. In addition to the generic, it’s available as the brand-name medications Levoxyl, Euthyrox, Levo-T, Unithroid, Synthroid, and Tirosint. The average retail price for a 1-month supply of generic levothyroxine ranges from $4 to $27., 5 Common Drugs That Are in Short Supply Right Now. Adderall, used for ADHD. Albuterol sulfate, used in inhalers for patients with lung diseases like asthma. Amoxicillin (oral powder suspension), an antibiotic. Cisplatin and carboplatin, chemotherapy drugs used to treat many cancers. Semaglutide (Ozempic and Wegovy), used to treat diabetes and ..., 4 days ago ... But what drug is currently in shortage? One example is levothyroxine – a synthetic thyroid hormone used to treat hypothyroidism. Levothyroxine ..., SYNTHROID: Common or Proper name: LEVOTHYROXINE SODIUM: Company Name: BGP PHARMA ULC: Market Status: MARKETED: Active Ingredient(s) ... ORAL ORAL: Packaging size: 90BT, 1000BT: ATC code: H03AA: ATC description: THYROID PREPARATIONS: Reason for shortage: Disruption of the manufacture of the drug. Anticipated start date: 2020-11-30: Actual start ..., 1-855-224-0231 or by e-mail at [email protected]. At Optum, we help create a healthier world, one insight, one connection, one person at a time. All Optum trademarks and logos are owned by Optum, Inc., in the U.S. and other jurisdictions. , DH activates shortage protocol for thyroid drug. The Government has issued a serious shortage protocol for levothyroxine 12.5mcg tablets in response to “significant ongoing disruption” to supply, the PSNC has said. The SSP, which is introduced today with immediate effect, allows pharmacists to substitute a 28-size pack of 25mcg tablets, one ..., The company’s analyses show a slight decrease below 95.0% of its labeled amount in levothyroxine sodium (T4) for some lots. This recall does not apply to TIROSINT® (levothyroxine sodium) capsules., Medicine notices Ngā pānui rongoā Details on supply issues, discontinuations, and brand changes. Pharmac funds nearly 1,000 medicines in over 2,000 presentations., Beth Mole - 4/12/2024, 3:20 PM. Enlarge. Getty | George Frey. 229. Drug shortages in the US have reached an all-time high, with 323 active and ongoing shortages already tallied …, Levothyroxine (Euthyrox, Synthroid, Levo-T, Unithroid, Levoxyl) is an inexpensive drug used to treat hypothyroidism.It also treats thyroid cancer.This drug is more popular than comparable drugs. Generic levothyroxine is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower. Get levothyroxine for as low as $6.90, which is 33% off the average retail ..., SYNTHROID: Common or Proper name: LEVOTHYROXINE: Company Name: BGP PHARMA ULC: Market Status: MARKETED: Active Ingredient(s) ... 90BT, 1000BT: ATC code: H03AA: ATC description: THYROID PREPARATIONS: Reason for shortage: Disruption of the manufacture of the drug. Anticipated start date: 2021-04-07: Actual start date: Estimated end date: 2021-05 ..., Serious Shortage Protocol: Levothyroxine tablets 12.5 microgram: Scotland: 01/03/2021: Class 3 Medicines Recall: Easyhaler Salbutamol Sulfate 100 micrograms per actuation/200 micrograms per actuation inhalation powder, EL (21)A/06: UK: 26/02/2021, The cost of levothyroxine without insurance starts at $4.00* for quantity of 75 mg and 30 tablets using an RxSaver coupon. The cost of levothyroxine can vary in price depending on the pharmacy your levothyroxine prescription is filled at. Below is a list of pharmacies and the starting cost of a levothyroxine prescription using an RxSaver coupon., Objective To describe the historical refinements, understanding of physiology and clinical outcomes observed with thyroid hormone replacement strategies. Methods A Medline search was initiated using the search terms, levothyroxine, thyroid hormone history, levothyroxine mono therapy, thyroid hormone replacement, combination LT4 therapy, levothyroxine Bioequivalence. Pertinent articles of ..., Last updated on Aug 14, 2023. Although the American Thyroid Association guidelines do not recommend taking Cytomel and Synthroid together, many people who are under the supervision of an internist/endocrinologist do take this combination treatment, prefer it, and have good results on it. Never take this combination without your doctor's advice ..., LEVOTHYROXINE SODIUM INJECTION: Common or Proper name: LEVOTHYROXINE SODIUM INJECTION: Company Name: FRESENIUS KABI CANADA LTD: ... Packaging size: 5 mL: ATC code: H03AA: ATC description: THYROID PREPARATIONS: Reason for shortage: Disruption of the manufacture of the drug. Anticipated start date: 2022-12-31: Actual start date: 2022-12-31 ..., Synthroid is a brand-name drug. Levothyroxine sodium is a generic medication. Other brand name drugs are Levothroid, Unithroid, Levo-T, Euthyrox, and Levoxyl. They are all synthetic thyroxine (T4) medications. T4 is made by the thyroid gland, to be converted into the T3 hormone.T3 plays a role in brain function, heart function, digestive ..., TIROSINT® (levothyroxine sodium) capsules, is a prescription medicine that contains a hormone called levothyroxine which is normally produced in your body by the thyroid gland. It is meant to replace the hormone to treat a condition called hypothyroidism. TIROSINT is not for use in people with temporary hypothyroidism caused by thyroiditis, or ..., Descriptions. Levothyroxine is used to treat hypothyroidism, a condition where the thyroid gland does not produce enough thyroid hormone. This medicine is also used to help decrease the size of enlarged thyroid glands (also called a goiter). Levothyroxine is also used together with surgery and radioiodine treatment to treat a type of thyroid ..., IPU Product File IPU Product File Medicines Shortages Update Medicines Shortages Update Last Updated 29 February 2024 Last Updated 29 February 2024 Tradename Pack Size GMS No Expected Resupply Date Manufacturer Date Notified Date Last Updated Date Resolved Reason Generic Name Note ABILIFY 7.5MG/ML SOLN FOR INJ 1.3ML 1VIAL 20th March 2024 OTSUKA 13-Feb-24 27-Feb-24 […], Of the 852 brain-dead donors who underwent randomization, 838 were included in the primary analysis: 419 in the levothyroxine group and 419 in the saline group. Hearts were transplanted from 230 ..., Levothyroxine is used to treat an underactive thyroid (hypothyroidism).It replaces or provides more thyroid hormone, which is normally produced by the thyroid gland. Low thyroid hormone levels can ..., In today’s digital age, we have access to an abundance of entertainment options right at our fingertips. From streaming services to podcasts, there is no shortage of content to enj..., ADHD Medicines- Shortage 202404. Bumetanide 5mg tablets- Shortage 202420 (login for website required) Capsaicin 0.025% (Zacin) and 0.075% (Axsain) cream- Shortage 202303 (login for website required) Carbamazepine (Tegretol) 200mg and 400mg prolonged release tablets- Shortage 202401 (login for website required), Levothyroxine is a synthetic thyroid hormone used to treat hypothyroidism, a condition in which the thyroid gland does not produce enough thyroid hormone. Learn about the dosing, indications, interactions, adverse effects, contraindications, and cost of Synthroid, Levoxyl, and other levothyroxine products on Medscape, a trusted source of medical information., Feb 7, 2022 ... Levothyroxine is indicated for replacement therapy in the management of demonstrated thyroid hormone deficiency, which includes: overt primary ..., The U.S. Food and Drug Administration (FDA) announced the NP Thyroid medication recall Sept. 17, the same day that Acella voluntarily recalled the products. According to the FDA, the recalled lots of NP Thyroid medication do not have enough of the active ingredient levothyroxine (T4). Because the levels of this drug may be as low as 87% of the ..., The number of drug products in short supply nearly doubled from start of 2022 to the end of last year, data obtained by the British Generic Manufacturers Association show. Around 50 drugs were on ..., This week: medications linked to compulsive behavior; symptoms caused by switching from generic levothyroxine to Synthroid; when will the atenolol shortage end. Joe and Teresa Graedon answer ..., Oral levothyroxine (LT4) is the standard therapy for patients with hypothyroidism. Oral LT4 is available in several formulations, including tablets, soft gel capsules and oral solution. ... In the Netherlands, there was a recent shortage of the most commonly used LT4 brand (Thyrax), resulting in a forced brand switch ...