How much acepromazine will kill a dog

Overview Multidrug Resistance 1 (MDR1) drug sensitivity is the result of a genetic variant that can place dogs at risk of severe or life-threatening complications after taking particular medications at specific doses. Treatment focuses on prevention by avoiding or lowering the dosages of drugs that may cause side effects in dogs who have this genetic variant. …

How much acepromazine will kill a dog. Dexmedetomidine is most often administered as an injection into the muscle, usually within the hospital setting. It can also be given as a gel or liquid by mouth (in dogs only) that is absorbed by the gums (gingiva) and is not to be swallowed. Your veterinarian will recommend how to time the dose. It is best to avoid feeding your dog after ...

The animal should be kept warm and quiet and closely monitored for responsiveness to stimuli and adequate breathing. IV fluids will help support blood pressure. If the affected animal is recumbent and severe respiratory depression has developed, the reversal agent flumazenil can be given at a dosage of 0.01 mg/kg, slow IV, in both cats and dogs ...

Acepromazine. Provides mild sedation at clinically prescribed dose (0.01 – 0.05 mg/kg IV, IM, SQ) Anti-arrhythmic. Requires at least 20 min for good effect even after IV injection, and 30 to 45 min when given IM, and longer for SQ. Prolonged duration.acepromazine 0.5-1.5 mg/kg IP. 60-120 minutes. Pentobarbital. 30-50 mg/kg IP. 90-120 minutes *Ketamine/xylazine without combination with an analgesic agent (opioid or NSAID) may be insufficient to produce a surgical plane of anesthesia. Administration of appropriate analgesic agents prior to surgery and/or addition of acepromazine will …In dogs, it is used mainly as a preanaesthetic and sedative agent, without the knowledge of pharmacokinetic data in this species. We studied the disposition both after oral and intravenous administration. It was shown, that the sedative effect after an oral dose of 1.3-1.5 mg/kg lasted for about 4 hours. The elimination was slower after oral ...Safely using acepromazine for your cat. When your veterinarian uses acepromazine, it may be in its injectable form. Tablets in 5-milligram, 10-milligram, and 25-milligram dosages make it handy for home administration. It takes approximately 45 minutes to an hour for the medicine to take effect, and when it does, the effects usually last …The dose for rodents is typically 5 mg/kg. For mice, it is assumed that most will weigh approximately 25‐30 grams. This can vary significantly between strains and with age. Dilute 0.1 mL of the manufacturer stock Carprofen (50 mg/mL) into 3.9 mL of sterile saline (0.9% NaCl).Work out how much of the following drugs (in ml) will be needed to anaesthetise Stig (answers are on the next page). Premedication: • Acepromazine –Dose rate: 0.04mg/kg –Concentration: 2mg/ml • Buprenorphine –Dose rate: 20μg/kg –Concentration: 0.3mg/ml Induction: • Alfaxalone –Dose rate: 2mg/kg –Concentration: 10mg/mlACP (Acepromazine maleate) 10mg Tablets for dogs and cats are used for anaesthetic premedication, tranquilisation, sedation and travel sickness. Anaesthetic premedication: Following acepromazine administration, the amount of anaesthetic dose necessary to induce anaesthesia is considerably reduced. This reduction is approximately one-third of …

The dosage of tramadol for dogs varies depending on their weight and the severity of the pain. The tramadol dosage for dogs is usually between 0.45 to 1.8 mg per pound of body weight (1mg to 5 mg/kg). The frequency varies depending on what you are giving it for. For general pain, it is given every 8 to 12 hours, but for cancer-related pain, …The diagnosis of tetanus is typically determined based on the presence and history of a wound on the dog, and how the dog appears to the vet (i.e., if the dog is showing any symptoms of tetanus ...GoodRx for Pets. We love our pets, but they can be expensive! It has been hard to compare prices on pet medications — until now. GoodRx brings together prices from major online pet medication retailers, local pharmacies and other sources to help find you the lowest prices on all your pet medications.This was a prospective, randomized, blinded, crossover study. Each of 6 dogs received 3 treatments at 1-week intervals. During all anesthetic episodes, dogs received 0.05 mg/kg BW acepromazine. Approximately 25 min later, dogs were given physiological saline (control) or tramadol [3 mg/kg BW (TR3) or 5 mg/kg BW (TR5)].Dogs: 0.5-1 mg Methadone HCl per kg body weight, SC, IM or IV (corresponding to 0.05-0.1 ml/kg) Cats: 0.3-0.6 mg Methadone HCL per kg body weight, IM (corresponding to 0.03-0.06 ml/kg) As individual response to methadone is varied, and depends partly on the dosage, the age of the patient, individual differences in pain sensitivity and general ...Dogs: 0.25-1.0 mg/lb of body weight. Dosage may be repeated as required. Animal safety: Acute and chronic toxicity studies have shown a very low order of toxicity for …

2.1. Horses. The study was approved by the Complutense University Animal Care and Use Committee. Six adult horses (two geldings and four mares) from our research herd, aged 4–22 years [mean age (±s.d.) of 13.2 ± 8.3 years] and with bodyweights ranging from 418–441 kg [mean (±s.d.) 425.8 ± 10.2 kg] were used in this study.How long does acepromazine last in a dog or cat? When the oral version of acepromazine is used for sedation or other stressful events, it is estimated to last approximately 1-4 hours. However, this medication can last for up to 24 hours after administration in some pets.Mar 9, 2022 ... Let them BE a dog or cat for their ... Jun 22, 2023 · 2.6K views. 05:50 ... Is Acepromazine the best solution to anxiety? May 18, 2023 · 111 ...No one has figured out what has made Sitapur's dogs so bloodthirsty all of a sudden. Over the past few weeks, villagers in Uttar Pradesh’s Sitapur district have been living in fear...

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Aug 25, 2022 · Safely using acepromazine for your cat. When your veterinarian uses acepromazine, it may be in its injectable form. Tablets in 5-milligram, 10-milligram, and 25-milligram dosages make it handy for home administration. It takes approximately 45 minutes to an hour for the medicine to take effect, and when it does, the effects usually last between ... Dogs: 0.25-1.0 mg/lb of body weight. Dosage may be repeated as required. Animal Safety: Acute and chronic toxicity studies have shown a very low order of toxicity for …The dogs were a mixed population of males and females, purebreds and mixed breeds, 0.25-13.4 years of age, weighing 1.8-57.7 kg. Methods: A prospective clinical trial in which the dogs were randomly assigned to one of three groups. All groups received acepromazine (0.05 mg kg(-1) intramuscularly (i.m.)).Introduction. Acepromazine is the phenothiazine derivative most commonly used for sedation in dogs. The drug has been found to possess antagonistic action at dopaminergic receptors within the brain; this may explain the mechanism by which acepromazine induces sedation ().Based on extensive data on the use of …The “Chill Protocol,” a management solution for reactive and fearful dogs, combines gabapentin with both melatonin and acepromazine to reduce a dog’s fearful or aggressive behavior at ...

Codeine (brand names: Codeine Contin®, Codeine Phosphate®, Codeine Sulfate®, Codeine 15 or 30) is an opioid medication used to treat mild to moderate pain, cough, and sometimes diarrhea. In the United States, codeine is considered a class II-controlled substance, which means there are strict rules regarding how it is prescribed, dispensed ...In a recent study in dogs ( 5 ), methadone at doses of 0.25, 0.5, and 0.75 mg/kg BW improved the sedation induced by acepromazine, the highest dose providing a longer …Simparica Trio is a combination medication that targets heartworm, fleas and ticks. It’s available for dogs up to 132 pounds in the following weight ranges: 2.8 to 5.5 pounds for $136.94 from Chewy. 5.6 to 11 pounds for $139.19 from Chewy. 11.1 to 22 pounds for $141.75 from Chewy. 22.1 to 44 pounds for $153.45 from Chewy. We present a case of intentional acepromazine overdose resulting in central nervous system and cardiovascular toxicity with confirmatory toxicokinetic data. Case report: A 54-year-old woman intentionally ingested 950 mg of her dog's acepromazine. Within 3 h of ingestion, she developed central nervous system and respiratory depression along with ... Overdoses happen. Sometimes, dogs get into things they shouldn’t, like medication, or well-meaning pet sitters or family members accidentally give dogs a higher dose than prescribed. These ...Lower doses of acepromazine should be used in dogs with MDR1 mutations, as well as giant breeds, greyhounds, and Boxers from UK-bred lines. If given at normal doses, the effect may be stronger and last longer in these breeds.The “Chill Protocol,” a management solution for reactive and fearful dogs, combines gabapentin with both melatonin and acepromazine to reduce a dog’s fearful or aggressive behavior at ...Giving acepromazine to your dog as you would a sedative to help with exposure to frightening noises and other issues can exacerbate your existing problem. Dosage of …Objectives: The aim of the present study was to quantify by accelerometry the trotting pattern of adult horses sedated with two different doses of acepromazine, in order to assess the use of this drug in equine lameness evaluations. Methods: Seven mature horses were used and three treatments were administered to each horse: saline solution, …

As an aid in tranquilization and as a preanesthetic agent in dogs. Acepromazine maleate tablets can be used as an aid in controlling intractable animals during examination, treatment, grooming, x-ray and minor surgical procedures. Dosage and administration: Dogs: 0.25 - 1.0 mg/lb of body weight. Dosage may be repeated as required.

The pharmacokinetics of acepromazine have been studied in several animal species, including dogs and equines (11–14). In the urine of horses, acepromazine and its metabolites can be detected for up to 48 h post intravenous injection ( 12 ).May 24, 2022 · Thankfully, there’s little to no risk of your dog ever dying as a result of acepromazine. Even in trials where dogs received up to 100mg/lb of the drug, there was no death. This being said, overdoses and adverse reactions can happen if dogs receive too many tablets, or if it’s not right for your dog. That’s exactly why it’s important to ... May 6, 2022 · 2.1. Horses. The study was approved by the Complutense University Animal Care and Use Committee. Six adult horses (two geldings and four mares) from our research herd, aged 4–22 years [mean age (±s.d.) of 13.2 ± 8.3 years] and with bodyweights ranging from 418–441 kg [mean (±s.d.) 425.8 ± 10.2 kg] were used in this study. The National Oceanic and Atmospheric Administration says there have been measurable effects and impacts from the biggest geomagnetic storm in decades.3. Vollmar AM. Immunoreactive N-terminal fragment of proatrial natriuretic peptide, ANP (1–98), in plasma of healthy dogs and dogs with impaired volume regulation: a comparison with the C-terminal ANP (99–126). Res Vet Sci. 1991;50(3):264–268. 4.Save 35% on your first Autoship order up to a maximum savings of $20.00 and 5% on recurring orders. Must be signed in to your Treats account to receive discount. Savings will automatically reflect in shopping cart with purchase of qualifying product and enrollment in Autoship. Exclusions apply.Objective: To compare sedative, cardiopulmonary, and adverse effects of 3 nalbuphine doses, administered alone or in combination with acepromazine, in dogs. Animals: 6 healthy dogs. Procedures: Dogs were administered nalbuphine (1.0, 1.5, or 2.0 mg/kg, intravenously [IV]) combined with physiologic saline solution (1 mL, IV; …Dogs: 0.25-1.0 mg/lb. of body weight. Contraindication: Phenothiazines may potentiate the toxicity of organophosphates. Therefore, do not use acepromazine ...Animals: A group of 40 dogs weighing mean (± standard deviation) 10.5 ± 6 kg, aged 2.6 ± 1.9 years. Methods: Dogs received either acepromazine 20 μg kg-1 (group A) or dexmedetomidine 2 μg kg-1 (group D) intramuscularly with methadone 0.3 mg kg-1. Anaesthesia was induced with propofol and maintained with sevoflurane.

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RMTC CTS Monograph Series: Acepromazine, October 2020 Acepromazine Background Acepromazine is a phenothiazine derivative widely used in equine veterinary medicine for mild sedation.i It is assigned a 3/B classification by the ARCI. Acepromazine can also be used as part of a pre-anesthetic protocol for surgical procedures.If your dog consumes food or drink with caffeine or theobromine in it, these chemicals can speed up the heart rate and stimulate their nervous systems. The risk of your dog becoming sick from ...Dogs: 0.25-1.0 mg/lb of body weight. Dosage may be repeated as required. Animal safety: Acute and chronic toxicity studies have shown a very low order of toxicity for …Buy Acepromazine Maleate Compounded Oral Liquid Apple Flavored for Dogs and Cats, 25-mg/mL, 30 mL at Chewy.com. FREE shipping and the BEST customer service! ... Acepromazine Maleate Compounded Oral Liquid for Dogs, Cats & Horses. By Acepromazine Maleate Compounded 1 Ratings. Rated 3 out of 5 stars. Prescription …Methods: Seven mature horses were used and three treatments were administered to each horse: saline solution, acepromazine (0.01 mg/kg), and acepromazine (0.02 mg/kg). The portable gait analyzer used consisted of three orthogonal accelerometers that measure accelerations along the dorsoventral, longitudinal, and lateral axes.Effects of acepromazine or dexmedetomidine on fentanyl disposition in dogs during recovery from isoflurane anesthesia Vet Anaesth Analg . 2016 Jan;43(1):35-43. doi: 10.1111/vaa.12271.Objective: To compare sedative, cardiopulmonary, and adverse effects of 3 nalbuphine doses, administered alone or in combination with acepromazine, in dogs. Animals: 6 healthy dogs. Procedures: Dogs were administered nalbuphine (1.0, 1.5, or 2.0 mg/kg, intravenously [IV]) combined with physiologic saline solution (1 mL, IV; …Get 20% off your first Chewy Pharmacy order with code GOODRX20. Save Now. Shop Acepromazine at Chewy Pharmacy and save even more with fast and free shipping on orders over $49. Sponsored by. info About GoodRx Prices. Prices. Medicare. Drug Info. Side Effects. ….

Acepromazine side effects for dog fear is something all dog owners should be aware of. As much as Acepromazine may seem effective, there are chances that this same drug meant to help your dog, will actually make matters much, much worse. When summer is in full swing, the chances for rain and thunderstorms significantly increase, causing many ...Dogs: 0.25-1.0 mg/lb of body weight. Dosage may be repeated as required. Animal Safety: Acute and chronic toxicity studies have shown a very low order of toxicity for acepromazine maleate.... how much more meaningful and rewarding veterinary anesthesia can be. ... Acepromazine can be used alone, as a premedicant. ... Dog. Acepromazine 0.005 to 0.060 mg/ ... Acepromazine Maleate Tablets are available in 10 and 25 mg quarter-scored tablets and are supplied in bottles containing 100 and 500 tablets. NDC 13985-583-10 – 10 mg – 100 tablets. NDC 13985-583-50 – 10 mg – 500 tablets. NDC 13985-582-25 – 25 mg – 100 tablets. NDC 13985-582-50 – 25 mg – 500 tablets. Manufactured for: MWI. Acepromazine Injection may be given intravenously, intramuscularly or subcutaneously. The following schedule may be used as a guide to IV, IM or SC injections: Dogs: 0.25–0.5 mg/lb of body weight Cats: 0.5–1 mg/lb of body weight Horses: 2–4 mg/100 lb of body weight. IV doses should be administered slowly, and a period of at least 15 ...As much as Acepromazine may seem effective, there are chances that this same drug meant to help your dog, will actually make things much, much worse. How …The comparison between the two experimental protocols showed that acepromazine affects tear production less in dogs. In contrast to Mouney et al. [ 4 ], the tear production after 20 min from the intramuscularly administrated acepromazine differed significantly from baseline readings, even though the STT 1 values did not reach the critical level ... PropoFlo (propofol) Indications. Propofol is an intravenous anesthetic injection for use in dogs as follows: 1. For induction of anesthesia. 2. For maintenance of general anesthesia for up to 20 minutes. 3. For induction of general anesthesia where maintenance is provided by inhalant anesthetics. How much acepromazine will kill a dog, A dosage that will only lightly anesthetize one strain may kill another. Dosages must be adjusted accordingly at the beginning of a project. Consult with the Veterinary staff during this process. RAT. Anesthesia *: Induce with Isoflurane at 2-4%, and maintain at 0.5-1.5% depending on procedure. Ketamine / Xylazine / Acepromazine cocktail:, Acepromazine Injection (acepromazine maleate, USP), a potent neuroleptic agent with a low order of toxicity, is of particular value in the tranquilization of dogs, cats and horses. Its rapid action and lack of hypnotic effect are added advantages. According to Baker, 1 the scope of possible applications for this compound in veterinary practice ..., Apr 14, 2021 ... Like most medications, it can come with side effects as well as benefits. Let's take a look into how this medication works, and what it's used ..., Effects of acepromazine or dexmedetomidine on fentanyl disposition in dogs during recovery from isoflurane anesthesia Vet Anaesth Analg . 2016 Jan;43(1):35-43. doi: 10.1111/vaa.12271., Kamata M, Nagahama S, Kakishima K, Sasaki N, Nishimura R.. Comparison of behavioral effects of morphine and fentanyl in dogs and cats. J Vet Med Sci 2012;74(2):231-234. Epstein M, Rodan I, Griffenhagen G, et al. 2015 AAHA/AAFP pain management guidelines for dogs and cats. JAAHA 2015;51(2):67-84. Smith JD, Allen SW, Quandt JE, Tackett RL., In dogs, it is used mainly as a preanaesthetic and sedative agent, without the knowledge of pharmacokinetic data in this species. We studied the disposition both after oral and intravenous administration. It was shown, that the sedative effect after an oral dose of 1.3-1.5 mg/kg lasted for about 4 hours. The elimination was slower after oral ..., Styrofoam is not digestible and can get stuck in the dog’s intestines, causing a blockage. If not treated, the blockage can kill the dog. Ingested Styrofoam can also cause damage t..., The diagnosis of tetanus is typically determined based on the presence and history of a wound on the dog, and how the dog appears to the vet (i.e., if the dog is showing any symptoms of tetanus ..., Equipped with incredibly strong jaws and sharp canine teeth, weasels kill chickens with one or more powerful bites to the head or neck. Weasels vary their tactics as necessary to s..., Acepromazine. 0.5–2 mg/kg, prn a to tid. 0.5–2 mg/kg, prn. Benzodiazepines. Alprazolam. 0.01–0.1 mg/kg, prn to qid. 0.125–0.25 mg/cat, prn to tid. Clonazepam. 0.1–1 mg/kg, bid-tid. 0.05–0.2 mg/kg, one to three times/day. Clorazepate. 0.5–2 mg/kg, prn to tid. 0.2–1 mg/kg, one to two times/day. Diazepam. 0.5–2 mg/kg, prn (eg ..., A dog suffering from metaldehyde poisoning is the type of emergency which will need immediate hospitalization and treatment. Unfortunately, there is no antidote available. The only course of treatment is to eliminate the metaldehyde from the dog's body. Your veterinarian will pump the dog's stomach and, if it is not convulsing, give …, Classically, laminitis is considered acute, subacute, or chronic. Acute laminitis is classically defined as the initial few days of clinical signs of laminitis (usually < 3 days) in a horse in which the distal phalanx has not undergone displacement. Subacute laminitis is commonly used to define laminitis in which clinical signs have continued >3 days, but the horse still …, No one has figured out what has made Sitapur's dogs so bloodthirsty all of a sudden. Over the past few weeks, villagers in Uttar Pradesh’s Sitapur district have been living in fear..., Acepromazine is available in 10 mg/ml injectable form. Acepromazine is also available in 5 mg, 10 mg and 25 mg tablets. Dosing Information of Acepromazine for Dogs and Cats. Medication should never be administered without first consulting your veterinarian. The usual oral dose of acepromazine is 0.5 to 1.5 mg per pound (1 to 3 mg/kg)., February 19, 2010. Acepromazine, often called simply Ace, is commonly used to tranquilize horses for veterinary procedures. However, its use in male horses can cause penile prolapse, or an ..., Fatal dog attacks, though rare, have risen sharply. Although 4.5 million Americans are bitten by dogs every year, according to the World Health Organization, being fatally …, Buprenorphine (brand names: Buprenex®, Simbadol®, Belbuca®, Vetergesic®, Buprenodale®, Sublocade®, Suboxone®, Subutex®, Temgesic®) is an opioid analgesic used to treat pain, or is used as a preanesthetic in the hospital or clinic setting. Its use in dogs, small mammals, large animals, and sometimes cats to treat pain is ‘off label ..., Acepromazine Maleate Tablets are available in 10 and 25 mg quarter-scored tablets and are supplied in bottles containing 100 and 500 tablets. NDC 13985-583-10 – 10 mg – 100 tablets. NDC 13985-583-50 – 10 mg – 500 tablets. NDC 13985-582-25 – 25 mg – 100 tablets. NDC 13985-582-50 – 25 mg – 500 tablets. Manufactured for: MWI. , Dogs with the P-glycoprotein (ie, MDR1 [ABCB1-1Δ]) gene deletion variant may be more sensitive to the tranquilizing effects of acepromazine, and duration of drug effects may be prolonged. When used at a dose of 0.1 …, Cephalic, lateral saphenous, and jugular veins are readily accessible in dogs for intravenous administration of drugs and fluids. Endotracheal Intubation Dogs are easily intubated with the use of a laryngoscope. Endotracheal tube sizes for 25-kg dogs are between 7.5 and 9 mm OD; for a 50-kg dog, sizes range from 10 to 15 mm OD., Work out how much of the following drugs (in ml) will be needed to anaesthetise Stig (answers are on the next page). Premedication: • Acepromazine –Dose rate: 0.04mg/kg –Concentration: 2mg/ml • Buprenorphine –Dose rate: 20μg/kg –Concentration: 0.3mg/ml Induction: • Alfaxalone –Dose rate: 2mg/kg –Concentration: 10mg/ml, 0.5mg/ml recipe based on a dose of 1mg/kg; stock drug: 5mg/mLmark up showing, Introduction. Acepromazine is the phenothiazine derivative most commonly used for sedation in dogs. The drug has been found to possess antagonistic action at dopaminergic receptors within the brain; this may explain the mechanism by which acepromazine induces sedation ().Based on extensive data on the use of …, Overdose of this drug will make a dog sleep for approximately 12 hours. More serious side effects may include hearing loss and seizure. Extreme overdose may ..., A dog suffering from metaldehyde poisoning is the type of emergency which will need immediate hospitalization and treatment. Unfortunately, there is no antidote available. The only course of treatment is to eliminate the metaldehyde from the dog's body. Your veterinarian will pump the dog's stomach and, if it is not convulsing, give …, Objectives: To compare reaction to injection, sedation and propofol induction dose in dogs receiving acepromazine-buprenorphine pre-anaesthetic medication by the intramuscular or subcutaneous routes. Methods: Fifty-two client owned dogs of American Society of Anesthesiologists grade I or II anaesthetised for diagnostic imaging. Dogs were …, b. Increase to 0.04 mg/kg in dogs and cats if greater sedation required. c. Can substitute acepromazine at 0.01–0.03 mg/kg dogs and 0.03–0.5 mg/kg cats (up to maximum 0.2 mg/kg dogs or cats) or alfaxalone at 2–5 mg/kg in cats. d. May provide anxiolytic, muscle relaxation and amnesic effect but may cause paradoxical excitation., If you think someone might have taken acepromazine, call Poison Control at 1-800-222-1222 right away or use the web POISON CONTROL ® online tool for help. Whether you call or log on, expert assistance is available 24 hours a day. Factors like the amount of drug taken, the person's body weight, and symptoms will be considered when deciding how ..., A safety study using elevated dosages of acepromazine maleate demonstrated no adverse reactions even when administered at three times the upper limit of the recommended daily dosage (3.0 mg/lb body weight). The clinical observation for this high dosage was mild depression which disappeared in most dogs 24 hours after termination of dosing., A dosage that will only lightly anesthetize one strain may kill another. Dosages must be adjusted accordingly at the beginning of a project. Consult with the Veterinary staff during this process. RAT. Anesthesia *: Induce with Isoflurane at 2-4%, and maintain at 0.5-1.5% depending on procedure. Ketamine / Xylazine / Acepromazine cocktail:, Get 20% off your first Chewy Pharmacy order with code GOODRX20. Save Now. Shop Acepromazine at Chewy Pharmacy and save even more with fast and free shipping on orders over $49. Sponsored by. info About GoodRx Prices. Prices. Medicare. Drug Info. Side Effects., Phenothiazines may be classed as tranquilizers, neuroleptics or antipsychotics. Acepromazine is the drug most commonly used and is licensed for use in the dog and cat in most countries. It is used to facilitate the handling or restraint of patients and is often employed as a premedicant prior to general anesthesia., This was a prospective, randomized, blinded, crossover study. Each of 6 dogs received 3 treatments at 1-week intervals. During all anesthetic episodes, dogs received 0.05 mg/kg BW acepromazine. Approximately 25 min later, dogs were given physiological saline (control) or tramadol [3 mg/kg BW (TR3) or 5 mg/kg BW (TR5)].