Nursing considerations for filgrastim

The most common side effects of pegfilgrastim are pain in the bones, arms, and legs. These are not all the possible side effects of this medication. Call your healthcare provider for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Learn and reinforce your understanding of Hematopoietic growth factors: Nursing pharmacology.Study with Quizlet and memorize flashcards containing terms like Which laboratory test will the nurse use to determine whether filgrastim (Neupogen) is effective for a patient with acute lymphocytic leukemia who is receiving chemotherapy? a. Platelet count b. Reticulocyte count c. Total lymphocyte count d. Absolute neutrophil count, A 68-year-old woman with acute myelogenous leukemia (AML ...Top 300 - Spring 2024 (P2) 61 terms. liud255. Preview. Respiratory Pharmacology Quiz Chapter 11. 35 terms. briannajane9. Preview. Study with Quizlet and memorize flashcards containing terms like Brand name, Therapeutic class, Pharmacologic class and more.Point of Care - Clinical decision support for Filgrastim. Treatment and management. Indications, Mechanism of Action, Administration, Adverse Effects, Contraindications, Monitoring, Toxicity, Enhancing Healthcare Team OutcomesFind information on Filgrastim (Granix, Neupogen) in Davis's Drug Guide including dosage, side effects, interactions, nursing implications, mechanism of action, half life, administration, and more. Davis Drug Guide PDF.Biosimilar filgrastim (Nivestim) is a 175-amino acid protein recombinant methionyl human G-CSF, with a molecular weight of 18,800 Da, that is produced in Escherichia coli . The active substance is non-glycosylated protein, containing an N-terminal methionyl extension. It stimulates the proliferation, differentiation and activation of late ...

However, the pandemic caused by SARS-CoV-2 has resulted in new considerations for cancer care and supportive care. Patients with cancer are a highly susceptible population at risk of transmission of SARS-CoV-2 and the potential consequences of the associated disease, COVID-19. ... Biosimilar filgrastim costs were …Easter 2021, our family portrait was via Skype. It’s the hardest part so far. I have trusted my mom voice to her nurses and gifted them her memory making days.... Edit Yo...Neutropenia refers to an abnormally low number of neutrophils in the blood. Normally, neutrophil count ranges from 2500 to 7500 neutrophils per microliter, but with neutropenia, it's usually less than. 1500 neutrophils per microliter of blood. Remember that neutrophils are a subtype of white blood cells that fight off bacterial and fungal ...Zarxio is a man-made form of a substance produced by the body known as granulocyte colony-stimulating factor (G-CSF). G-CSF stimulates the growth of neutrophils, a type of white blood cell that helps the body fight against infection. Man-made forms of naturally occurring substances are known as biosimilars.Pegfilgrastim is a pegylated granulocyte colony-stimulating factor that is FDA-approved to decrease the risk of patients developing febrile neutropenia when receiving myelosuppressive chemotherapy regimens. For primary prophylaxis, the risk of developing febrile neutropenia should be 20% or higher, and there should be no other safer regimen …Granulocyte colony-stimulating factor (G-CSF)—filgrastim, filgrastim-sndz, tbo-filgrastim, or pegfilgrastim—is indicated for the prevention of chemotherapy-induced neutropenia in patients ...

GRANIX is a prescription medicine: used in adults and children 1 month of age and older with certain types of cancer (non-myeloid malignancies), who are receiving chemotherapy that affects the bone marrow. given to help decrease the length of time that the number of certain white blood cells (neutrophils) are very low (severe neutropenia).Administration. Give with a full glass of water if allowed. Store syrup formulations in tight, light-resistant containers at 15° 30° C (59° 86° F) unless directed otherwise. Microenema: Insert full length of nozzle (half length for children) into the rectum. Squeeze entire contents of tube and remove completely before releasing grip on tube.Pediatric. Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of filgrastim-sndz injection in children. Safety and efficacy have been established in children with severe chronic neutropenia.Administration Alerts. • Give oral calcium supplements with meals or within 1 hour following meals. • Administer IV calcium slowly to prevent hypotension, dysrhythmias, and cardiac arrest. Interactions-• Labs: Decreased K+, Phosphorus, Mg. • Foods: alcohol, caffeine, carbonated beverages affect absorption; oxalic acid in spinach ...Antineoplastic Agents, Phytogenic. Topotecan. Topotecan (Hycamtin, SmithKline Beecham, Philadelphia, PA) was approved by the U.S. Food and Drug Administration in 1996 for use in relapsed ovarian cancer and in 1999 for platinum-sensitive small-cell lung cancer. Hematologic toxicity has been the predominant side effect associated with its use.Ackley and Ladwig’s Nursing Diagnosis Handbook: An Evidence-Based Guide to Planning Care. We love this book because of its evidence-based approach to nursing interventions. This care plan handbook uses an easy, three-step system to guide you through client assessment, nursing diagnosis, and care planning.

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Protamine sulfate is an antidote for standard heparin and LMWHs. In other words,Treatment of severe heparin over dosage and low molecular weight heparin over dosage. Side Effects/Adverse Effects. Severe hypotension, cardiovascular collapse, noncardiogenic pulmonary edema, catastrophic pulmonary vasoconstriction, and pulmonary hypertension.Pegfilgrastim is a pegylated granulocyte colony-stimulating factor that is FDA-approved to decrease the risk of patients developing febrile neutropenia when receiving myelosuppressive chemotherapy regimens. For primary prophylaxis, the risk of developing febrile neutropenia should be 20% or higher, and there should be no other safer regimen that is equally effective available to the patient.Filgrastim-sndz is the first biosimilar drug approved in the USA; the reference product is filgrastim (NEUPOGEN). It is a white blood cell growth factor that regulates the production of neutrophils in the bone marrow and affects neutrophil proliferation, differentiation, and some end-cell functions.Nursing Implications. Assessment & Drug Effects. Obtain a careful history of dietary intake and drug and alcohol usage prior to start of therapy. Drugs reported to cause folate deficiency include oral contraceptives, alcohol, barbiturates, methotrexate, phenytoin, primidone, and trimethoprim. Folate deficiency may also result from renal dialysis.

Drug Name Generic Name : guaifenesin Brand Name:Allfen; AMBI 1000, 1200; Diabetic Tussin; Hytuss; Hytuss 2X; Liquibid; Mucinex; Muco-Fen; Organidin NR; Robitussin, Scot-Tussin Expectorant; Siltussin SA Classification: Expectorant Pregnancy Category C Dosage & Route Available forms : Syrup—100 mg/5 mL; liquid—100, 200 mg/5 mL; capsules—200 mg; tablets—100, 200, 400 mg; ER tablets—600 ...Study with Quizlet and memorize flashcards containing terms like The nurse administers filgrastim (Neupogen) to the client. The nurse explains that this drug is used in the treatment of: a) Acute lymphoblastic leukemia. b) Neutropenia, or neutropenia secondary to chemotherapy. c) Clients with Hodgkin's disease who are having bone marrow …These are vital nursing interventions done in patients who are taking systemic antifungals: Check culture and sensitivity reports to ensure that this is the drug of choice for this patient. Ensure that patient receives full course of antifungals as prescribed (may take up to 6 months for chronic infection), to get the full beneficial effects. ...Zarxio is a man-made form of a substance produced by the body known as granulocyte colony-stimulating factor (G-CSF). G-CSF stimulates the growth of neutrophils, a type of white blood cell that helps the body fight against infection. Man-made forms of naturally occurring substances are known as biosimilars.Administration Alerts. • Give oral calcium supplements with meals or within 1 hour following meals. • Administer IV calcium slowly to prevent hypotension, dysrhythmias, and cardiac arrest. Interactions-• Labs: Decreased K+, Phosphorus, Mg. • Foods: alcohol, caffeine, carbonated beverages affect absorption; oxalic acid in spinach ...fever, abdominal pain, back pain, feeling unwell. swelling of stomach area or other swelling, decreased urination, trouble breathing, dizziness, tiredness. Pegfilgrastim injection products may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.Filgrastim and pegfilgrastim are used to assist recovery in patients with low white blood cell counts. This article explores the dosing, efficacy, cost, and clinical considerations of filgrastim and pegfilgrastim in neutropenia care. Increased knowledge of the medications may contribute to positive patient outcomes.Find information on Filgrastim (Granix, Neupogen) in Davis's Drug Guide including dosage, side effects, interactions, nursing implications, mechanism of action, half life, administration, and more. Davis Drug Guide PDF. Download the app! ... Nursing Central is an award-winning, complete mobile solution for nurses and students. ...Find information on Filgrastim (Granix, Neupogen) in Davis's Drug Guide including dosage, side effects, interactions, nursing implications, mechanism of action, half life, administration, and more. Davis Drug Guide PDF.Intramuscular penicillin G benzathine is indicated in the treatment of infections due to penicillin-G-sensitive microorganisms that are susceptible to the low and very prolonged serum levels common to this particular dosage form. Therapy should be guided by bacteriological studies (including sensitivity tests) and by clinical response.What are the Indications for FILGRASTIM-SNDZ? 1 INDICATIONS AND USAGE ZARXIO is a leukocyte growth factor indicated to: ‚Ä¢ Decrease the incidence of infection‚Äö as manifested by febrile neutropenia‚Äö in patients with nonmyeloid malignancies receiving myelosuppressive anti‚Äëcancer drugs associated with a significant incidence ...Three nursing considerations for filgrastim are: 1) do not agitate the vial, 2) monitor CBC twice a week, 3) Do not freeze-store in the refrigerator. Discard if left at room temp more than 24hrs. 10. A nurse is caring for a client who has refused his morning medications.

Adults—6 milligrams (mg) as a single injection under the skin once every cancer treatment cycle. Children weighing more than 45 kilograms (kg)—Dose is based on body weight and must be determined by your doctor. It is usually 6 milligrams (mg) as a single injection under the skin once every cancer treatment cycle.

Filgrastim is used to prevent or reduce the risk of infections while you are being treated with cancer medicines. This medicine is also used to help the bone marrow recover after a bone marrow transplantation, for a process called peripheral blood progenitor cell collection in cancer patients, and to improve survival in cancer patients …Pain and anxiety are additional symptom management considerations. Filgrastim-associated back pain should be managed with appropriate analgesic support. Anti-anxiolytics in conjunction with complementary therapies may be used to effectively manage anxiety and pain. ... The Oncology Nursing Society (ONS) is a professional association …Filgrastim side effects. Get emergency medical help if you have signs of an allergic reaction: hives, sweating, rash, dizziness, fast heart rate, wheezing, difficult breathing, swelling of your face, lips, tongue, or throat.. Filgrastim can cause a serious lung problem called acute respiratory distress syndrome (ARDS) and a rare but serious side effect called capillary leak syndrome.0.5 to 1 mEq/kg/dose (maximum dose 30 mEq) potassium chloride for injection diluted in an appropriate amount and type of solution to be intravenously infused once at a rate not to exceed 0.3 to 0.5 mEq/kg/hour. Oral: 2 to 5 mEq/kg/day orally in equally divided doses using age-appropriate oral dosage formulations.Aspirin Nursing Interventions. Several nursing interventions for aspirin may be appropriate and these may include: 1. Use the lowest effective dose of aspirin for the shortest period of time. Using the lowest dose of aspirin or lower than those used previously is still sufficient to exert a maximum inhibitory effect on platelet function.Study with Quizlet and memorize flashcards containing terms like A nurse is assessing a client who is postoperative following an outpatient endoscopy procedure using midazolam. The nurse should monitor for which of the following findings as an indication that the client is ready for discharge?, A nurse is caring for a client who is receiving filgrastim.Oct 15, 2023 · Filgrastim in the pharmaceutical name for granulocyte colony-stimulating factor (G-CSF). Pegfilgrastim is the long-acting form of filgrastim. Eflapegrastim is a closely related G-CSF analogue. The excretion of exogenous G-CSF into breastmilk or its effects on breastfed infants have not been well studied. Limited data indicate that filgrastim and a similar G-CSF product, lenograstim, are poorly ...

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Find information on Filgrastim (Granix, Neupogen) in Davis’s Drug Guide including dosage, side effects, interactions, nursing implications, mechanism of action, half life, …A. Assess for bone pain. B. Assess for right lower quadrant pain. C. Auscultate for crackling in the bases of the lungs. D. Auscultate the chest to listen for a heart murmur. A. Assess for bone pain. Study with Quizlet and memorize flashcards containing terms like examples of Erythopoietic growth factors, indications for epoetine alfa, mode of ...epoetin alpha (Epogen, Procrit) classification. hematopoietic growth factor. epoetin alpha (Epogen, Procrit) side effects. HTN, pure red cell aplasia, seizures if BP & Hct rise rapidly, HA, fever, nausea, diarrhea, edema, BBW: ↑ risk for cardiovascular and thromboembolic events. epoetin alpha (Epogen, Procrit) nursing considerations.Information obtained from Kaplan NCLEX-RN Drug Guide Sixth Edition ISBN:978-1-62523-114-7 Learn with flashcards, games, and more — for free.inflammation of your blood vessels - numbness or tingling, skin rash, fever, headache, body aches, night sweats, weight loss, feeling or weak or tired; or. kidney problems - swelling, urinating less, feeling tired or short of breath. Common Neupogen side effects may include: fever, pain, cough, trouble breathing;Read this chapter of Davis's Drug Guide for Rehabilitation Professionals online now, exclusively on F.A. Davis PT Collection. F.A. Davis PT Collection is a subscription-based resource from McGraw Hill that features trusted content from the best minds in PT.Infections, other health conditions and exposure to chemicals can also lead to severely low neutrophil levels. Causes of acquired agranulocytosis include: Autoimmune diseases, including lupus and rheumatoid arthritis. Bone marrow disease and bone marrow failure disorders like aplastic anemia. Cancers that affect your bone marrow, like leukemia.Neupogen ® (filgrastim) is a drug that has been used successfully for cancer patients to stimulate the growth of the white blood cells, making patients less vulnerable to infections, it is expected to help patients who have bone marrow damage from very high doses of radiation in much the same way. A person who has received a very high dose of ...Find the best online master's in nursing administration online with our list of top-rated schools that offer accredited online programs. Updated June 2, 2023 • 0 min read thebestsc...Nursing Assessment. Heparin is a commonly used medication in various healthcare settings, primarily to prevent and treat blood clots. As a nurse, it is essential to perform a comprehensive nursing assessment before administering heparin to ensure safe and effective patient care. 1. Review patient’s medical history.At a nursing home, skilled staff and health care providers offer around-the-clock care. Nursing homes can provide a number of different services: At a nursing home, skilled staff a... ….

Teaching points. Take this drug exactly as prescribed. Do not take a higher dosage. Avoid alcohol, sleep-inducing, or over-the-counter drugs; these may cause dangerous effects. You may experience these side effects: Drowsiness, dizziness, blurred vision (avoid driving or engaging in activities that require alertness); dyspepsia (take drug with ...Hematopoietic Growth Factors Leukopoietic Growth Factors Filgrastim (Granulocyte Colony-Stimulating Factor - G-CSF)/Neupogen. ... Nursing Considerations. monitor WBC count do not shake vial (denatures protein) Sets found in the same folder. cholestyramine/Questran. 3 terms. melody4lifexd4. colestipol/Colestid.Find information on Filgrastim (Granix, Neupogen) in Davis's Drug Guide including dosage, side effects, interactions, nursing implications, mechanism of action, half life, administration, and more. Davis Drug Guide PDF.Epoetin Alfa 8/9. If you have questions or concerns, contact your healthcare provider. A member of your care team will answer Monday through Friday from 9 a.m. to 5 p.m. Outside those hours, you can leave a message or talk with another MSK provider. There is always a doctor or nurse on call.Evidence-based US guidelines provide recommendations for the use of granulocyte colony-stimulating factor (G-CSF) as supportive therapy in patients with cancer receiving chemotherapy. Pegfilgrastim is recommended for FN prophylaxis in patients with non-myeloid malignancies receiving a high-risk chem …Pegfilgrastim is approved to reduce the chance of infection in adults and children with: Neutropenia caused by myelosuppressive chemotherapy for non- myeloid cancer. Pegfilgrastim is a form of filgrastim that has polyethylene glycol (PEG) attached to it. This form stays in the body longer than does filgrastim, so it doesn't need to be given ...Signs of kidney problems like unable to pass urine, change in how much urine is passed, blood in the urine, or a big weight gain. Signs of lung or breathing problems like shortness of breath or other trouble breathing, cough, or fever. Dark urine. Chest pain or pressure or a fast heartbeat . Dizziness or passing out.Find information on Filgrastim (Granix, Neupogen) in Davis's Drug Guide including dosage, side effects, interactions, nursing implications, mechanism of action, half life, administration, and more. Davis Drug Guide PDF.Nursing Management. There are a couple of nursing management and considerations that nurses have to keep in mind when taking care of a client with leukemia. Radiation and Chemotherapy. These are primarily given to decrease the abnormally high number of white blood cells. Radiation and chemotherapy will technically restart the entire system of ...Teach the patient/family about the signs and symptoms of lactic acidosis (such as hyperventilation, fatigue, malaise, chills, myalgia, somnolence). Then, instruct to seek immediate medical attention and stop taking metformin. Educate the patient regarding increased risk of lactic acidosis with alcohol consumption. Nursing considerations for filgrastim, Here is a table of commonly encountered antiplatelet, anticoagulant, and thrombolytic agents, their generic names, and brand names: Antiplatelet Agents. acetylsalicylic acid (Aspirin, Aspro Clear, Disprin, Bayer Aspirin) cilostazol (Pletal) dipyridamole (Persantine) tirofiban (Aggrastat) Anticoagulants., Find information on Filgrastim (Granix, Neupogen) in Davis's Drug Guide including dosage, side effects, interactions, nursing implications, mechanism of action, half life, administration, and more. Davis Drug Guide PDF., Nursing Management. There are a couple of nursing management and considerations that nurses have to keep in mind when taking care of a client with leukemia. Radiation and Chemotherapy. These are primarily given to decrease the abnormally high number of white blood cells. Radiation and chemotherapy will …, Filgrastim is capable of reducing the incidence and severity of neutropenia and the complications that accompany it in patients with cancer or HIV infection. Although there are few data evaluating the effect of treatment with granulocyte colony-stimulating factor on quality of life, it is assumed that the benefits would be seen through both the ..., Filgrastim is a medication that is used to stimulate the production of white blood cells in patients undergoing chemotherapy or bone marrow transplantation. As a nurse, it is important to be aware of the nursing considerations for filgrastim in order to provide the best possible care for your patients., This medicine may affect certain lab tests. Tell all of your health care providers and lab workers that you take filgrastim-sndz. This medicine may cause a severe and sometimes deadly problem called capillary leak syndrome (CLS). CLS may lead to low blood pressure , abnormal heartbeat, chest pain, or heart attack., Notes. Immunostimulants or immune stimulants are drugs that energize the immune system when it is exhausted from fighting prolonged invasion or when the immune system needs help fighting a specific pathogen or cancer cell. It is one of the classifications of drug class called immunomodulators. Immunomodulators, as the name implies, are drugs ..., Being a nurse is not only a rewarding profession in terms of helping others, but it also offers competitive compensation. However, many people wonder how much being a nurse actuall..., 3 Nursing Considerations For Filgrastim on Newsflare 3 Nursing Considerations For Filgrastim ..., ANGIOMAX RTU is a direct thrombin inhibitor indicated for use as an anticoagulant in patients undergoing percutaneous coronary intervention (PCI), including patients with heparin-induced thrombocytopenia and heparin-induced thrombocytopenia and thrombosis syndrome. ( 1 ) View Our Nursing Pharmacology Course. References: https://open.fda.gov/. , Neupogen® stimulates the growth of neutrophils, a type of white blood cell, which are important immune cells that fight infection caused by bacteria, viruses or fungus. Neutrophils can be damaged by chemotherapy and leave patients susceptible to severe infection. Neupogen® works by binding to areas on immature blood cells, which stimulates ..., Examples of nursing philosophies include fostering a healing environment for patients, treating others with compassion and respect, and advocating for patient rights. A nursing phi..., Ondansetron Nursing Pharmacology. Ondansetron is a medication that is most commonly used to prevent nausea and vomiting, primarily caused by cancer treatments like chemotherapy and radiation therapy. It is also used to prevent nausea and vomiting in post-operative patients. Ondansetron is classified as a serotonin 5-HT3 …, Administration. Give with a full glass of water if allowed. Store syrup formulations in tight, light-resistant containers at 15° 30° C (59° 86° F) unless directed otherwise. Microenema: Insert full length of nozzle (half length for children) into the rectum. Squeeze entire contents of tube and remove completely before releasing grip on tube., Purpose. Filgrastim (NEUPOGEN ®) is the originator recombinant human granulocyte colony-stimulating factor widely used for preventing neutropenia-related infections and mobilizing hematopoietic stem cells.This report presents findings of a systematic literature review and meta-analysis of efficacy and safety of originator filgrastim to update previous reports., TBO-FILGRASTIM (GRANIX) Nursing Considerations. View the FULL Outline. When you start a FREE trial you gain access to the full outline as well as: SIMCLEX (NCLEX Simulator) 6,500+ Practice NCLEX Questions; 2,000+ HD Videos; 300+ Nursing Cheatsheets; Start Free Trial "Would suggest to all nursing students . . . Guaranteed to ease the stress!", Filgrastim is a medication that is used to stimulate the production of white blood cells in patients undergoing chemotherapy or bone marrow transplantation. As a nurse, it is important to be aware of the nursing considerations for filgrastim in order to provide the best possible care for your patients., Find information on Filgrastim (Granix, Neupogen) in Davis's Drug Guide including dosage, side effects, interactions, nursing implications, mechanism of action, half life, administration, and more. Davis Drug Guide PDF. Download the app! ... Nursing Central is an award-winning, complete mobile solution for nurses and students. ..., Study with Quizlet and memorize flashcards containing terms like indication, adverse effects, contraindications and more., Filgrastim side effects. Get emergency medical help if you have signs of an allergic reaction: hives, sweating, rash, dizziness, fast heart rate, wheezing, difficult breathing, swelling of your face, lips, tongue, or throat.. Filgrastim can cause a serious lung problem called acute respiratory distress syndrome (ARDS) and a rare but serious side …, Lithium potentiates release of neutrophils Monitor CBC twice a week during treatment. : Nursing Interventions Give a lower dose or stop treatment for a WBC above 10,000/mm3. Monitor the degree of bone pain. Monitor temperature. Give acetaminophen (Tylenol) or opioid analgesics. ... Administer filgrastim by intermittent or continuous IV infusion ..., These are vital nursing interventions done in patients who are taking local anesthetics: Prepare emergency equipment to maintain airway and provide mechanical ventilation if needed. Ensure that patients receiving spinal anesthesia or epidural anesthesia are well hydrated and remain lying down for up to 12 hours after the anesthesia to minimize ..., The 2020 coronavirus pandemic certainly reminded the world of the importance of quality nursing. If you’re interested in training to become a nurse but don’t have the schedule flex..., Neupogen ® (filgrastim) is a drug that has been used successfully for cancer patients to stimulate the growth of the white blood cells, making patients less vulnerable to infections, it is expected to help patients who have bone marrow damage from very high doses of radiation in much the same way. A person who has received a very high dose of ..., FILGRASTIM, G-CSF (fil GRA stim) is a granulocyte colony-stimulating factor that stimulates the growth of neutrophils, a type of white blood cell (WBC) important in the body's fight against infection. It is used to reduce the incidence of fever and infection in patients with certain types of cancer who are receiving chemotherapy that affects ..., All countries currently using filgrastim are urged to audit current usage to determine if under-dosing is commonplace, by number of doses and/or weight, and the implications of this on planned chemotherapy schedules and RDI (See Online Resource 1 in the electronic supplementary material for a suggested minimum dataset)., A neutropenic client is receiving filgrastim, a granulocyte colony-stimulating factor (G-CSF) used for stimulating neutrophil production, often after chemotherapy or for mobilizing hematopoietic stem cells for procedures such as a transplant. There are several nursing considerations for this medication:, Filgrastim in the pharmaceutical name for granulocyte colony-stimulating factor (G-CSF). Pegfilgrastim is the long-acting form of filgrastim. Eflapegrastim is a closely related G-CSF analogue. The excretion of exogenous G-CSF into breastmilk or its effects on breastfed infants have not been well studied. Limited data indicate that filgrastim and a similar G-CSF product, lenograstim, are poorly ..., A. Assess for bone pain. B. Assess for right lower quadrant pain. C. Auscultate for crackling in the bases of the lungs. D. Auscultate the chest to listen for a heart murmur. A. Assess for bone pain. Study with Quizlet and memorize flashcards containing terms like examples of Erythopoietic growth factors, indications for epoetine alfa, mode of ..., Nursing Considerations. • May cause seizures, tremors, hypertension, hepatotoxicity, diarrhea, N/V, gingival hyperplasia. • Increases immune suppression with corticosteroids. • Avoid grapefruit juice while taking this medications. • Assess for signs of organ rejection. • Monitor renal panel, liver enzymes. • Take medication as directed., NOVOLOG MIX 70/30 is a mixture of insulin aspart protamine, an intermediate-acting human insulin analog, and insulin aspart, a rapid-acting human insulin analog, indicated to improve glycemic control in adult patients with diabetes mellitus. Limitations of Use: ‚Ä¢ Not recommended for the treatment of diabetic ketoacidosis., The most common side effects of pegfilgrastim are pain in the bones, arms, and legs. These are not all the possible side effects of this medication. Call your healthcare provider for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088., Filgrastim is a medication that is used to stimulate the production of white blood cells in patients undergoing chemotherapy or bone marrow transplantation. As a nurse, it is important to be aware of the nursing considerations for filgrastim in order to provide the best possible care for your patients.